Use of Isotretinoin in Pregnancy

The most important study on the mechanisms involved in acne treatment and causing acne development. effective drug, Isotretinoin; It is a derivative of vitamin A in the retinoid group and has been used since 1982. all over the world with the approval of FDA (US Food and Drug Administration) and 1983 EMA (European Medicines Agency) widely used. In addition to the treatment of acne in different intensities, many different skin types The most important side effect of isotretinoin, which is used in the treatment of disease, is "teratogenicity". “If used during pregnancy, it causes congenital anomalies in the baby”. Therefore, this drug absolutely cannot be used durıng pregnancy. This condition prescribes medication It is well known by physicians, and patients are informed before the drug is started. In order to further increase safety and security, the special After the forms are signed, the medication is started. At each prescribing, these forms It is obligatory to fill in the form and pharmacies are prohibited from dispensing the drug without these forms. These submitted forms are kept for at least 10 years.

Another important point to be aware of in this regard is that approximately 1 month after the drug is discontinued. It is quickly cleared from the body. There is no storage in the body. Therefore, it is recommended that patients using isotretinoin become pregnant 1 month after stopping the drug. there is no problem. There is absolutely no side effect of the drug such as infertility. all this The information is scientifically proven. In conclusıon; Medications containing isotretinoin should be administered under appropriate contraception. should be used and should not become pregnant during the treatment. 1 month after discontinuation of the drug (maximum any congenital anomaly in case of conception after the recommended period of 35 days) There is no risk of development.